Biological Safety Program

To protect individuals from the risks associated with the use, storage, and handling of biohazardous material, and to ensure compliance with the U.S. Department of Health and Human Service; Possession, Use, and Transfer of Select Agents; the United States Government Policy for Institutional Oversight of Dual Use Research of Concern, and the National Institutes of Health “Guidelines for Research Involving Recombinant DNA Molecules”, Syracuse University has established requirements for biological research in the Biological Safety Program.

1.0 Roles and Responsibilities

1.1 Institutional Biosaftey Commitee

1.2 Biosafety Officer

1.3 Dean, Directors and Departments Heads

1.4 Principal Investigator

1.5 Laboratory Personnel


2.0 Research Requirements

2.1 Biological Material

2.2 Recombinant DNA Research

2.3 Select Agents

2.4 Animals

2.5 Human Blood and Cell Lines


3.0 Laboratory Practices

3.1 Biosafety Levels

3.2 Housekeeping

3.3 Standard Operating Procedure

3.4 Chemical Disinfectants

3.5 PPE Requirements

3.6 Accident Procedure

3.7 Emergency Procedures

3.8 Reporting Incidents

3.9 Investigation of Accidents

3.10 Spill Response Procedure

3.11 Disposal of Biological Waste

3.12 Designated Areas

3.13 Decommissioning

3.14 Material Transfers


4.0 Laboratory Equipment

4.1 Biosafety Cabinets

4.2 Biosafety Cabinet Certification

4.3 Procedures for Centrifugation

4.4 Syringes and Needles

4.5 Pipettes

4.6 Blenders, Mixers, Sonicators, and Cell Disruption Equipment


5.0 Medical Assistance

5.1 Medical Restrictions


6.0 Select Agents

6.1 Select Agent Review Process

6.2 Training

6.3 Security Measures

6.4 Facility Requirements

6.5 Possession of Exempt Quantities


7.0 References


Attachments

Attachment A – Biological Agents and Assigned Biosafety Levels [XLS, 97KB]

Attachment B – Select Agents

Attachment C – Recombinant DNA Review Requirements

Attachment D – Biosafety Levels and Criteria

Attachment E – Guidelines for Work with Toxins of Biological Origin

Attachment F – Select Agent Security Plan [DOC, 50KB]

Attachment G – Procedures for Transferring Select Agents

Attachment H – Regulated Medical Waste Disposal Policy [DOC, 57KB]

Attachment I – Biological Material Transfer Form [DOC, 25KB]

Attachment K – Human Pathogens/Select Agent Possession and Use Application Form [DOC, 72KB]

Attachment L – Biological Safety Assessment Form [DOC, 168KB]

Attachment M – Recombinant DNA Notification Form

Attachment N – SOP Template [DOC, 119KB]

Attachment O – Biological Toxin Safety Assessment Form [DOC, 120KB]