(LCDC-96) – Biosafety Level was assigned to pathogen based on recommendations made by the Laboratory Center for Disease Control as outlined in “Laboratory Biosafety Guideline” 2nd Edition 1996
(EU-96) – Biosafety Level was assigned to the pollutant based in the recommendations made by the European Union as outlined in the European Economic Community Directive 93/88
(Belgium-97) – Biosafety Level was assigned to the pathogen based on recommendations made nu the Belgium government as outlined in the Decree of Brussels Region of 26 February 2002
*Biosafety level 3 practices are recommended for work involving production quantities or concentration of cultures and for activities with high potential for areosol production
Genus | Species | Comments | SU 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Acinetobacter | | was Herellea vaginicola, A. calcoaceticus ssp.anitratus | 2 | | 2 |
Acinetobacter | lwoffi | formerly Mima polymorpha | | | |
Actinobacillus | actinomycetemcomiana | genus Hemophilus | 2
| | 2 |
Actinobacillus | spp | EC-Haemophilus actinomycetem comitans | 2
| | 2 |
Actinomadura | madurae | | 2(EU -96)
| | |
Actinomadura | pelletieri | | 2(EU-96)
| | |
Actinomyces | bovis | | 2(Belguim-97)
| | |
Actinomyces | gerencseriae | | 2(EU-96)
| | |
Actinomyces | israelii | | 2(EU-96)
| | |
Actinomyces | naeslundii | | | | |
Actinomyces | pyogenes | was Corynebacterium | 2 | | 2 |
Actinomyces | spp | | 2 | | |
Aeromonas | hydrophilia | | 2(EU-96) | | 2 |
Aeromonas | punctata | | 2(Belguim-97) | | |
Aeromonas | spp | | | | |
Afpia spp | | | | | |
Amycolata | autotrophica | | 2 | | 2 |
Arachnia | propionica | was Propionibacterium propionicum | | | |
Arcanobacterium | haemolyticum | was Corynebacterium | 2 | | 2 |
Arcanobacterium | equi | was Corynebacterium | 2(EU-96) | | |
Arizona | hinshawii | | 2 | | 2 |
Genus | Species | Comments | SU 2004 Biosafety Level | BMBL - 1993 CDC Biosafety Level | NIH rDNA - 1996 Biosafety Level |
Bactillus | anthracis | SELECT AGENT | 2/3* | 2/3* | 2 |
Bactillus | cereus | | 2 | | |
Bactillus | thuringiensis | | 2(Belguim-97) | 2 | |
Bacteroides | fragilis | | 2(EU-96) | | |
Bacteroides | spp | | 2(Belguim-97) | | |
Bartonella | bacilliformis | | 2(LCDC-96) | | |
Bartonella | elizabethae | | 2(LCDC-96) | | |
Bartonella | spp | | | | |
Bartonella | henselae | was genus Rochalimaea | 2 | | 2 |
Bartonella | quintana | was genus Rochalimaea | 2 | 2 | 2 |
Bartonella | vinsonii | was genus Rochalimaea | 2 | 2 | 2 |
Bordetella | all spp | | 2 | | 2 |
Bordetella | bronchiseptica | | 2 | | 2 |
Bordetella | parapertussis | | 2 | | 2 |
Bordetella | pertussis | | 2 | 2 | 2 |
Borrelia | burgdorferi | | 2 | | 2 |
Borrelia | duttoni | | 2(EU-96) | | |
Borrelia | recurrentis | | 2 | | 2 |
Borrelia | spp | | 2(EU-96) | | |
Borrelia | vincenti | | 2(LCDC-96) | | |
Brucella | abortus | SELECT AGENT | 3 | 3 | 3 |
Brucella | canis | | 3 | 3 | 3 |
Brucella | melitensis | SELECT AGENT | 3 | 3 | 3 |
Brucella | ovis | | 3 | | 3 |
Brucella | spp | except B. ovis | 3 | 3 | 3 |
Brucella | suis | | 3 | 3 | 3 |
Burkholderia | spp | Australia, EU still as Pseudomonas spp. | 3 | | |
Burkholderia | mallei | was Pseudomonas | 3 | | 3 |
Burkholderia | pseudomallei | was Pseudomonas | 3 | | |
Genus | Species | Comments | SU 2004 Biosafety Level | BMBL 1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Calymmatobacterium | granulomatis | | | | |
Campylobacter | coli | | 2 | 2 | 2 |
Campylobacter | fetus | subsp fetus | 2 | 2 | 2 |
Campylobacter | jejuni | | 2 | 2 | 2 |
Campylobacter | spp | | 2 | 2 | 2 |
Campylobacter | sputorum | | 2(LCDC-96) | | |
Capnocytophaga | spp | | | | |
Cardiobacterum | hominis | | 2(EU-96) | | |
Chlamydia | pneumoniae | | 2 | | 2 |
Chlamydia | psittaci | avian strains, 3 | 2 | 2 | 2 |
Chlamydia | spp | C. pneumoniae*, EU=2, Belgium=2 | 2 | 2 | |
Chlamydia | trachomatis | lymphogranuloma venereum agent | 2 | 2 | 2 |
Citrobacter | spp | | 2 | | |
Clostridium | botulinum | SELECT AGENT | 2 | 2 | 2 |
Clostridium | chauvoei | | 2 | | 2 |
Clostridium | difficile | | 2(LCDC-96) | | |
Clostridium | equi | | 2(Belgium-97) | | |
Clostridium | haemolyticum | | 2 | | 2 |
Clostridium | histolyticum | | 2 | | 2 |
Clostridium | novyi | | 2 | | 2 |
Clostridium | perfringens | | 2(LCDC-96) | | |
Clostridium | septicum | | 2 | | 2 |
Clostridium | sordelli | | 2(LCDC-96) | | |
Clostridium | spp | | 2 | | 2 |
Clostridium | tetani | | 2 | 2 | 2 |
Corynebacterium | bovis | | 2(EU-96) | | |
Corynebacterium | diphtheriae | | 2 | 2 | 2 |
Corynebacterium | matruchotii | | 2(EU-96) | | |
Corynebacterium | minutissimum | | 2(EU-96) | | 2 |
Corynebacterium | pseudotuberculosis | | 2 | | |
Corynebacterium | renale | | 2 | | 2 |
Corynebacterium | spp | | 2 | | 2 |
Corynebacterium | ulcerans | | 2(EU-96) | | |
Coxiella | burnetii | SELECT AGENT | 3 | 3 | 3 |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Dermatophilus | congolensis | | 2 | | 2 |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Edwardsiella | tarda | | 2 | 2 | 2 |
Eikenella | corrodens | | 2 | | |
Enterobacter | aerogenes/cloacae | | 2(EU-96) | | |
Enterobacter | spp | | 2(EU-96) | | |
Enterococcus | spp | (Streptococcus faecalis) | 2(EU-96) | | |
Erlichia | sennetsu | (Rickettsia) | 2(EU-96) | | |
Erlichia | spp | | 2(EU-96) | | |
Erysipelothrix | rhusiopathiae | was spp insidiosa | 2 | 2 | 2 |
Erysipelothrix | spp | | | | |
Escherichia | coli | (pathogenic strains) | 2 | | 2 |
Escherichia | coli K12 | genetically crippled | 1 | | 1 |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Flavobacterium | meningosepticum | was Legionella | 2(EU-96) | | |
Flavobacterium | spp | | | | |
Fluoribacter | bozemanae | | 2(EU-96) | | |
Francisella | novocida | | 2(LCDC-96) | | |
Francisella | tularensis | Type A SELECT AGENT | 3 | 3 | 3 |
Francisella | tularensis | Type B | 2 | | 2 |
Fusobacterium | necrophorum | | 2(LCDC-96) | | |
Fusobacterium | spp | | | | |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Gardnerella | vaginalis | | 2(EU-96) | | |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Haemophilus | ducreyi | | 2 | | 2 |
Haemophilus | influenzae | | 2 | | 2 |
Haemophilus | spp | | 2(EU-96) | | |
Hartmanella | spp | | | | |
Helicobacter | pylori | was genus Campylobacter | 2 | 2 | 2 |
Herellea
| vaginicola | see Actinetobacter baumannii | 2 | | 2 |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Haemophilus | ducreyi | | 2 | | 2 |
Haemophilus | influenzae
| | 2 | | 2 |
Haemophilus
| spp | | 2(EU-96) | | |
Hartmanella | spp | | | | |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Lactobacillus | spp | | 2 | 2 | 1 |
Legionella
| pneumophila | | 2 | 2 | 2 |
Legionella | spp | | 2 | 2 | 2 |
Legionella-like organisms | | | 2 | 2 | |
Leptospira | interrogans | all serotypes (icterohemorragiae) | 2 | | |
Listeria | ivanovii | | 2 | | 2 |
Listeria | monocytogenes | | 2 | | 2 |
Listeria | spp | | 2 | | 2 |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Mima | polymorpha | Acinetobacter lwoffi | 2 | | |
Moraxella | spp | | 2 | | |
Morganella | morganii | | 2(EU-96)
| | |
Mycobacterium | africanum | | 2 | | 2 |
Mycobacterium | asiaticum | | 2 | 2 | 2 |
Mycobacterium | avium-intracelluare | (avium in Canada) | 2 | 2 | 2 |
Mycobacterium | bovis | BCG is 2 | 2 | 2 | 2 |
Mycobacterium | chelonei | EU chelonae | 2 | 2 | 2 |
Mycobacterium | fortuitum | | 2 | 2 | 2 |
Mycobacterium | kansasii | | 2 | 2 | 2 |
Mycobacterium | leprae | | 2 | 2 | 2 |
Mycobacterium | malmoense | | 2 | 2 | 2 |
Mycobacterium | marinum | | 2 | 2 | 2 |
Mycobacterium | microti | | 2 | 2 | 2 |
Mycobacterium | paratuberculosis | Mycobacterium avium subsp. Paratuberculosis | 2 | 2 | 2 |
Mycobacterium | scrofulaceum | | 2 | 2 | 2 |
Mycobacterium | simiae | | 2 | 2 | 2 |
Mycobacterium | spp | except. MDR M.tb complex | 2 | 2 | 2 |
Mycobacterium | szulgai | | 2 | 2 | 2 |
Mycobacterium | tuberculosis | 3, V,T for multiply resistant | 3 | 3 | 3 |
Mycobacterium | ulcerans | | 2 | 2 | 2 |
Mycoplasma | xenopi | | 2 | 2 | 2 |
Mycoplasma | hominis | | 2 | | 2 |
Mycoplasma | mycoides | SELECT AGENT | select agent | | restricted |
Mycoplasma | pneumoniae | | 2 | | 2 |
Mycoplasma | agalactiae | restricted animal pathigen | restricted | | restricted |
Mycoplasma | spp | | | | |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Neisseria | gonorrhoeae | | 2 | | 2 |
Neisseria | meningitidis | | 2 | | 2 |
Neisseria | spp | | 2(Belgium-97) | | |
Nocardia | asteroides | | 2 | | 2 |
Nocardia | brasiliensis | | | | 2 |
Nocardia | caviae | | 2(EU-96) | | |
Nocardia | farcinica | | 2(EU-96) | | |
Nocardia | nova | | 2 | | |
Nocardia | spp | | 2 | | |
Nocardia | transvalensis | | 2 | | |
Nocardia | otitidis-caviarum | EU-otitidiscaviarum | 2 | | 2 |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Pasteurella | haemolytica | | 2 | | 2 |
Pasteurella | multocida | | 3 | | 3 |
Pasteurella | pneumotropica | | 2(LCDC-96) | | |
Pasteurella | spp | type B, "buffalo", other virulent strains | 2 | | 2 |
Peptostreptococcus
| anaerobius | | 2(EU-96) | | |
Plesiomonas | shigelloides | | 2(EU-96) | | |
Porphyromonas | spp | | 2(EU-96) | | |
Prevotella | spp | | 2(EU-96) | | |
Proteus | mirabilis | | 2(EU-96) | | |
Proteus | penneri | | 2(EU-96) | | |
Proteus | spp. | | 2(EU-96) | | |
Proteus | vulgaris | | 2(EU-96) | | |
Providencia | alcalifaciens | | 2(EU-96) | | |
Providencia | rettgeri | | 2(EU-96) | | |
Providencia | spp | | 2(EU-96) | | |
Pseudomonas | aeruginosa | | 2 | | 2 |
Pseudomonas | spp | except P. mallei, Burholderia maiiei | | | |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Rhodococcus | equi | | 2 | | 2 |
Rickettsia | (vole)
| | 2 | | 2 |
Rickettsia | akari | | 3 | 3 | 3 |
Rickettsia | australis | | 3 | 3 | 3 |
Rickettsia | canada | | 3 | 3 | 3 |
Rickettsia | conorii | | 3 | 3 | 3 |
Rickettsia | montana | | 3(LCDC-96) | | |
Rickettsia | mooseri | see R. typhi | 3(LCDC-96) | | |
Rickettsia | parkeri | | 3(LCDC-96) | | |
Rickettsia | prowazekii | SELECT AGENT | 3 | 3 | 3 |
Rickettsia | rhipicephali | | 3 | | |
Rickettsia | rickettsii | SELECT AGENT | 3 | 3 | 3 |
Rickettsia | sennetsu | | 3 | | 3 |
Rickettsia | sibirica | | 3 | | 3 |
Rickettsia | spp | | 3 | | 3 |
Rickettsia | tsutsugamushi | | 3 | 3 | 3 |
Rickettsia | typhi (mooseri) | | 3 | | 3 |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Salmonella | arizonae | | 2 | | 2 |
Salmonella | cholerasuis | | 2 | | 2 |
Salmonella | enteritidis | | 2 | | 2 |
Salmonella | gallinarum-pullorum | | 2 | | 2 |
Salmonella | meleagridis | | 2 | | 2 |
Salmonella | paratyphi,A,B,C | A,B,C | 2 | | 2 |
Salmonella | spp | all spp and serotypes/ serovars | 2 | | 2 |
Salmonella | typhi | | 2 | | 2 |
Salmonella | typhimurium | | 2 | | 2 |
Serpulina | spp | | 2(EU-96) | | |
Serratia | marcescens | | | | |
Serratia | liquefaciens | | | | |
Shigella | boydii | | 2 | 2 | 2 |
Shigella | dysenteriae | Type 1 | 2 | 2 | 2 |
Shigella | flexneri | | 2 | 2 | 2 |
Shigella | sonnei | | 2 | 2 | 2 |
Shigella | spp | | 2 | 2 | 2 |
Sphaerophorus | necrophorus | | 2 | | 2 |
Staphylococcus | aureus | | 2 | | 2 |
Staphylococcus | epidermidis | | 2(EU-96) | | |
Streptobacillus | moniliformis | | 2 | | 2 |
Streptobacillus | spp | | 2 | | 2 |
Streptococcus | agalactiae | | 2 | | 2 |
Streptococcus | pneumoniae | | 2 | | 2 |
Streptococcus | pyogenes | Canada Lancefield Groups A-D, G | 2 | | 2 |
Streptococcus | spp | see also Enterococcus spp | 2 | | 2 |
Streptococcus | suis | | 2 | | 2 |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Treponema | carateum | | 2(EU-96) | | |
Treponema | pallidum | | 2 | | 2 |
Treponema | pertenue | | 2 | 2 | 2 |
Treponema | spp | | 2(LCDC-96) | | |
Treponema | vincentii | | 2(LCDC-96) | | |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Ureaplasma | urealyticum | | 2(LCDC-96) | | |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Vibrio | cholerae | including El Tor(EU, Belgium) | 2 | 2 | 2 |
Vibrio | parahaemolyticus | | 2 | 2 | 2 |
Vibrio | spp | | 2 | 2 | 2 |
Vibrio | vulnificus | | 2 | | 2 |
Genus | Species | Comments | Syracuse University 2004 Biosafety Level | BMBL-1993 CDC Biosafety Level | NIH rDNA-1996 Biosafety Level |
Yersinia | enterocolitica | | 2 | | 2 |
Yersinia | pestis | SELECT AGENT | 3 | 3 | 3 |
Yersinia | pseudotuberculosis | | 2 | | |
Yersinia | spp | except Y. pestis | 2 | | |